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Hericium erinaceus, also known as "Lion's Mane," is a medicinal mushroom known for its neuroprotective properties. A recent study published in Evidence-Based Complementary and Alternative Medicine explored its impact on mood and sleep quality in overweight or obese patients.
The study was conducted at the Obesity Center of the Luigi Devoto Occupational Health Clinic , part of the IRCCS Fondazione Policlinico di Milano . It involved 77 overweight or obese adult volunteers with mood or sleep disorders or compulsive eating .
📍 Where: Milan, Italy
🗓️ When: Study completed in 2019, with supplementation for 8 weeks
💊 How: Each participant took Hericium erinaceus extract orally , while also following a controlled low-calorie diet.
Before and after administration, the researchers monitored:
Symptoms of anxiety, depression and insomnia through questionnaires
Blood levels of BDNF (brain-derived neurotrophic factor) and pro-BDNF , biomarkers linked to mental health
After 8 weeks, a significant reduction in anxiety and depressive symptoms , improved sleep , and increased pro-BDNF levels were observed , suggesting potential neuronal regeneration.
👉 Read the full study on PubMed Central
Hericium erinaceus appears to influence levels of BDNF (Brain-Derived Neurotrophic Factor), a protein involved in neuronal plasticity and mood regulation. Increased BDNF is associated with improvements in depression and anxiety.
Study participants reported improved sleep quality, with reduced insomnia and deeper, more restful sleep.
This study suggests that Hericium erinaceus may be a valuable supplement for improving mood and sleep quality, especially in overweight or obese individuals. Its effect on BDNF and its ability to improve sleep make it a promising nutraceutical supplement.
At JUN, we believe in the power of nature, backed by science. We offer high-quality Hericium erinaceus extract capsules, ideal for supporting mental well-being and improving sleep quality.
👉 Find out more about junlei.it
Note: This article is based on the study “Hericium erinaceus Improves Mood and Sleep Disorders in Patients Affected by Overweight or Obesity: Could Circulating Pro-BDNF and BDNF Be Potential Biomarkers?” published in Evidence-Based Complementary and Alternative Medicine .